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Catechin Hydrate

NAME: Catechin hydrate [Acacia catechu extract]

Catechin is a polyphenolic flavonoid which has been isolated from a variety of natural sources including tea leaves, grape seeds, and the wood and bark of trees such as acacia and mahogany. Catechin has the ability to suppress the effects of Parkinson’s and Alzeimer’s disease. Catechin is a more potent antioxidant than ascorbate or α-tocopherol in certain in vitro assays of lipid peroxidation.

Potential Uses

  • Anti-obese
  • Anti-cancer activity
  • Catechin hydrate & HIV-1

Anti – obese:

Catechin hydratein diabetic rate has shown to be beneficial in reducing obesity and in improving plasma parameters. (Mehra 2010)

Anti – cancer activity:

Catechin hydrate, possesses anticancer activity is based on the ability to induce apoptosis. It also suppressed the growth of breast cancer cells without significant toxicity, making it a promising chemotherapeutic agent for breast cancer treatment (Ali A., 2010).

Catechin hydrate and HIV-1:

In a formulation study catechin hydrate has shown adjuvant effect in immune responses against the gp120 protein of HIV-1(CN54). Also in a combination of two mucosal and two systemic vaccinations of mice, the study has found significant enhancement of both local and systemic antibodies as well as cytokine responses.


Product Name ChocoPure [Catechin]
Botanical Name Acacia catechu
Plant part Heart wood
Standardization Catechin & Epicatechin
S. No. Parameters Specification Method
1 Description White to Cream colored powder Visual
2 Identification To comply by HPLC KVN/QC/STP-IN/007
3 Loss on drying NMT 5.0% USP <731>
4 Residue on Ignition NMT 3.0% USP <281>
5 Solubility Soluble in Water KVN/QC/STP-GT/039
6 Water by KF NMT 5.0% w/w USP<921>
7 Tapped bulk density 0.30-0.50 g/ml USP <616>
Sieve test (passes through)
8 # 20 mesh NLT 95.0%w/w USP <786>
9 Purity by HPLC
[% Areas of Catechin & Epicatechin]
NLT 95.0% Purity on dry basis KVN/QC/STP-IN/007
10 Assay By HPLC
Content of Catechin
Content of Epictechin

50.0 - 60.0% w/w on dry basis
15.0 -20.0% w/w on dry basis

Heavy Metals
Lead NMT 5.0ppm ICP-OES
Arsenic NMT 1.0ppm ICP-OES
Cadmium NMT 0.3ppm ICP-OES
Mercury NMT 0.1ppm ICP-OES
12 Residual solvents Should comply by ICH/USP USP <467>
Microbiological Profile
Total plate count NNMT 5000cfu/g USP <2021>
Yeast and molds count NMT 100cfu/g USP <2021>
Escherichia coli Absent /10g USP <2022>
Salmonella Absent /10g USP <2022>
Staphylococcus aureus Absent /10g USP <2022>
Pseudomonas aeruginosa Absent /10g USP <62>